Beyond NEEDLES

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Beyond NEEDLES

Nano-channelling offers an advanced route to transdermal delivery. The team at Zemits explains how

In modern aesthetics, clients are seeking visible results without discomfort, trauma, or downtime. This demand has led to a new era of innovation in transdermal delivery systems, enabling deeper penetration of active ingredients through the skin barrier without needles.

From microneedles and sonophoresis to electroporation, these modalities have transformed how practitioners deliver rejuvenation. Yet one technology stands out for its precision, safety, and comfort:

DermeDrop, integrated into the Zemits Verstand HD Pro system, provides an intelligent, needle-free approach to mesotherapy.

The skin barrier challenge

The skin, our largest organ, is remarkably effective at protecting the body from environmental aggressors. Its outermost layer, the stratum corneum, forms a resilient barrier composed of densely packed keratinocytes and intercellular lipids. While this structure prevents transepidermal water loss and pathogen invasion, it also limits the penetration of beneficial actives from skincare products.

Traditional mesotherapy and microneedling have long been used to bypass this limitation by mechanically puncturing the skin to deliver nutrients, peptides, and growth factors into the dermis via microchannels.

However, these methods involve discomfort, risk of irritation, and downtime, which can deter clients seeking gentle yet effective rejuvenation. The evolution of transdermal delivery aims to solve this problem by enhancing permeability without breaking the skin’s integrity.

Nano-channelling: the science of DermeDrop

Electroporation is a biophysical process that temporarily increases skin permeability using brief, controlled electrical pulses. These pulses create transient aqueous channels within cell membranes, allowing active molecules to pass through lipid barriers that would otherwise resist penetration. Once the electrical field is removed, the skin’s natural structure rapidly returns to normal, ensuring both safety and reversibility.

The DermeDrop applicator enhances this mechanism with a refined nano-channelling design that stimulates the skin’s surface with a smooth, atraumatic tip. Unlike microneedles, these nano-protrusions do not puncture or wound the epidermis.

Instead, they work synergistically with electroporation to form microchannels that enable deep delivery of active ingredients into the dermal layers.

This combination delivers exceptional absorption efficiency while maintaining client comfort and complete epidermal integrity. The result is a needle-free treatment that delivers measurable improvements in hydration, tone, and elasticity, with minimal contraindications.

The Verstand HD Pro System

At the heart of this innovation is the Zemits Verstand HD Pro, a multifunctional platform that delivers a comprehensive approach to skin rejuvenation. The system integrates six advanced modalities, including radiofrequency skin tightening, Hydrodiamond skin resurfacing, ultrasonic peeling, and oxygen revitalisation.

This versatility allows practitioners to create highly personalised protocols tailored to each client’s unique skin condition and goals.

Within the Verstand HD Pro, the DermeDrop applicator is critical to advanced transdermal infusion. Its ergonomic design and precision control ensure that each serum is delivered evenly, while energy settings can be finely tuned to suit various skin sensitivities and treatment depths. By maintaining optimal energy flow and serum diffusion, Verstand HD Pro ensures consistent results and enhanced treatment safety.

This design reflects the core Zemits philosophy: intelligent technology that respects the biology of the skin.

Meso-Cocktails: science in every drop

For optimal results, DermeDrop works synergistically with the Zemits professional mesotherapy serum formulations, which are designed for effective electroporation delivery. Each serum targets specific skin concerns, allowing aestheticians to personalise their treatments with precision:

• Zemits PeptiElixir: A rejuvenating peptide complex that stimulates collagen synthesis and supports cellular regeneration. Ideal for mature and tired skin, it promotes firmness and visible rejuvenation.

• Zemits RevitaCollagen: A hydrating formula enriched with collagen and moisturising factors to restore elasticity and radiance, leaving skin supple and deeply nourished.

• Zemits AcnoLex: A purifying serum designed for acne-prone or congested skin. Its antibacterial and sebum-regulating properties help calm inflammation and support skin clarity.

When delivered through the Derme Drop technique, these formulas penetrate the skin more effectively than topical application alone. The result is a visible improvement in texture, hydration, and tone after just a few sessions, with no pain, downtime or risk of adverse reactions.

The future of needle-free mesotherapy

The integration of Verstand HD Pro, DermeDrop technology, and Zemits’ Meso-Cocktails allows practitioners to combine the precision of energy-based skincare with the power of active biochemistry.

Beyond rejuvenation, the technology’s gentle mechanism supports barrier repair, acne management, and preventative skin health, making it suitable for a wide demographic of clients

For aesthetic professionals, it offers a future-ready solution that combines efficacy, comfort, and innovation in a single intelligent platform.

In the new landscape of advanced skincare, needle-free does not mean compromise. With systems like Zemits Verstand HD Pro and DermeDrop technology, practitioners can deliver transformative results while preserving the skin’s natural integrity.

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